The importance of taking BOSULIF as prescribed by your doctor or healthcare professional (HCP)
- Not taking your medicine as prescribed can impact how it works. It is
important to take your medicine exactly as prescribed by your doctor or HCP. - Only your doctor or HCP can tell you if changes to your dosage are
appropriate in managing your therapy.
BOSULIF is available in 400-mg, 500-mg, and 100-mg tablets and is taken once
a day with food.
Your doctor or HCP most likely started you on a dosing
schedule of taking one 400-mg tablet a day with food if you are newly diagnosed or one
500-mg tablet a day with food if you were resistant or intolerant to prior therapy. This
can vary, though, depending on your individual needs. Your doctor or HCP may adjust your
dose or tell you to stop taking BOSULIF if there are issues or concerns about tolerability.
ONLY YOUR DOCTOR OR HCP CAN TELL YOU IF CHANGING
YOUR DOSE IS APPROPRIATE IN MANAGING YOUR THERAPY
What is a dose adjustment?
BOSULIF is available in 400–mg, 500–mg, and 100–mg tablets to allow for dose adjustments. A dose adjustment is when your
doctor or HCP changes the amount of BOSULIF you’re taking, in order to best tailor your therapy to your individual needs.
Your doctor or HCP may change your dose of BOSULIF or tell you to stop taking BOSULIF depending on how you are doing
on treatment, as it may help manage side effects and response to treatment.
How Should I Take BOSULIF?
It is important to take BOSULIF exactly as prescribed by your doctor. Follow the instructions below and talk
with your doctor or HCP for more information.
Make Sure to Take BOSULIF as Prescribed
When you take BOSULIF...
Make sure to tell your doctor or healthcare professional (HCP) of any changes in:
Start a routine
- Take your medicine at the same time every day. Consider taking BOSULIF in the morning with breakfast or in
the evening with dinner. - Use alarms and calendars as reminders to take medicine.
- Use a pill container to organize your medicines at home and when you travel.
Your doctor or HCP can help you with side effects
When you start treatment, consider asking your doctor how to prepare for possible episodes of diarrhea, the most
common side effect of BOSULIF.
doctor, lifestyle management, and
monitoring over time may help
you manage
side effects.
What Should I Tell My Doctor?
- have liver problems
- have heart problems
- have kidney problems
- have high blood pressure
- have diabetes
- are pregnant or plan to become pregnant. BOSULIF can harm your unborn baby. Tell your doctor or HCP right away if you
become pregnant while taking BOSULIF- Females who are able to become pregnant should have a pregnancy test before starting treatment with BOSULIF and
should use effective birth control (contraception) during treatment with BOSULIF and for at least 2 weeks after the last
dose. Talk to your doctor or HCP about birth control methods that may be right for you
- Females who are able to become pregnant should have a pregnancy test before starting treatment with BOSULIF and
- are breastfeeding or plan to breastfeed. It is not known if BOSULIF passes into your breast milk or if it can harm your baby.
Do not breastfeed during treatment with BOSULIF and for at least 2 weeks after the last dose
Tell your doctor or HCP about all the medicines you take, including prescription medicines, over-the-counter medicines,
vitamins, and herbal supplements. When taken together, BOSULIF and certain other medicines can affect each other. Know the
medicines you take. Keep a list of your medicines and show it to your doctor or HCP and pharmacist when you get a
new medicine.
Tell your doctor or get medical help right away if you get respiratory tract infections, loss of appetite, headache, dizziness,
back pain, joint pain, rash, or itching while taking BOSULIF. These may be symptoms of a severe allergic reaction.
Your doctor may change your dose, temporarily stop, or permanently stop treatment with BOSULIF if you have certain side effects.
BOSULIF may cause fertility problems in females and males. This may affect your ability to have a child. Talk to your doctor if this is a concern for you.
Also let your doctor or HCP know about:
- any changes in your medicines or any new medicines you start taking.
- any side effect that bothers you or that does not go away
- changes in your lifestyle, including any new health issues that may arise
- how you are feeling, even if you think it is not related to your CML
Ongoing communication can help you and your doctor or HCP work together to best manage your CML. Make sure you are following up with your doctor or HCP regularly, regardless of how you are feeling.
Frequent monitoring and blood tests are very important, so ask your doctor or HCP about getting tests that assess the status of your disease and how you are responding to treatment.
If you have diarrhea, call your doctor or HCP. Your doctor or HCP may recommend you take medicine to treat diarrhea. Always talk to your doctor or HCP before taking any over-the-counter medicines. Your doctor or HCP may change your dose, temporarily stop, or permanently stop treatment with BOSULIF to help manage diarrhea.
Tell your doctor or HCP if you have any side effect that bothers you or that does not go away. For more information, ask your doctor, HCP, or pharmacist.